Basic Info.
Application
Internal Medicine
Product Name
Griseofulvin tablet
Pharmaceutical Technology
Chemical Synthesis
Specification
125mg; 500mg
Product Description
Product Description
Product name: Griseofulvin tablet
Character:
This product is white or almost white.
Indications:
This product is applicable to the treatment of various ringworm diseases, including tinea capitis, tinea beard, tinea corporis, tinea cruris, tinea pedis and onychomycosis. The above mentioned tinea is caused by dark red tinea, tinea truncata, tinea trichophyta, tinea interdigitata, etc., as well as microspore audouan, microspore canis, microspore gypsioides, and dermatophyte flocculus, etc.
This product should not be used in patients with mild disease, limited superficial fungal infection and local use of antifungal drugs that have been effective. Griseofulvin has no effect on candida, histoplasmosis, actinomycetes, sporotrichum, blastomycetes, coccidia, nocardia and cryptococcus infections and tinea versicolor.
Adverse reactions:
1. Nervous system headache is relatively common, and about 10% of patients may have headache, which is relatively serious at the beginning, and can be alleviated by continuous medication. Others still have lethargy and fatigue. Occasionally, dizziness, ataxia and peripheral neuritis occur.
2. A few patients with digestive system may have upper abdominal discomfort, nausea or diarrhea, which is generally mild and can be tolerated by patients.
3. About 3% of patients with allergic reactions may develop skin rash, occasionally angioneurotic edema, persistent urticaria, exfoliative dermatitis, and a few patients may develop photosensitive dermatitis.
4. This product can occasionally cause leukopenia in peripheral blood picture, and occasionally cause hepatotoxicity and proteinuria.
Matters needing attention:
1. Cross allergy Because griseofulvin is obtained from penicillium, it is speculated that the drug may have cross allergy with penicillin or penicillamine. However, this condition has not been confirmed clinically, but patients with penicillin allergy still need to be cautious and closely observed when using this product.
2. Griseofulvin has tumorigenic effect in animal experiments.
3. This product can occasionally cause hepatotoxicity. People with original liver disease or liver function damage should weigh the pros and cons before deciding whether to use the drug.
4. This product can induce porphyria and lupus erythematosus. If patients with lupus erythematosus have indications to use this drug, they must weigh the advantages and disadvantages before deciding.
5. During the treatment, the peripheral blood picture, liver function, blood urea nitrogen, creatinine and urine routine should be detected regularly.
6. This product can be taken at the same time or after meals, and the best one is to eat a high-fat meal, because it can reduce gastrointestinal reactions and increase drug absorption.
7. In order to prevent recurrence, treatment should continue until clinical symptoms disappear and laboratory tests confirm that the pathogenic bacteria have been completely eradicated. The general course of treatment is: tinea capitis for 8-10 weeks; Tinea corporis for 2-4 weeks; Tinea pedis for 4 to 8 weeks; Fingernail ringworm for at least 4 months; Tinea toenail for at least 6 months; However, the recurrence rate of tinea toenail is still high.
8. Usually, appropriate local medication should be given at the same time, which is particularly important for tinea pedis.
9. Male patients should take contraceptive measures during and at least 6 months after treatment.
Taboo:
Porphyria, liver failure, pregnant women and those allergic to this product are forbidden.
Overdose:
In case of overdose, symptomatic treatment and supportive treatment are mainly adopted, such as gastric lavage, emesis and fluid replacement.
Pharmacology and toxicology:
This product mainly has good antibacterial effect on superficial fungi such as Trichophyton, Microsporium and Epidermis. It has no antibacterial effect on candida, cryptococcus, histoplasmosis, sporotrichum, blastomycetes, coccidiospores, etc. The drug line inhibits the growth of fungi by interfering with their nucleic acid synthesis.
Storage:
Closed storage.
Detailed Photos
Company Profile
ARTHA GROUP
The manufacturer and developer of high quality medicine and APIs that benefit human health.
OUR VERSION
ARTHA group is the manufacturer and developer of high quality medicine and APIs that benefit human health, we are committed to supplying quality products for using in the pharmaceutical, healthcare and veterinary industries.
OUR MISSION
ARTHA group is to create more value for our clients, to provide a comprehensive range of customized value-added services and products and to meet each client's specific requirements.
OUR PRODUCTSDrug Impurity |
Tablets |
Suppositories |
Solution(Lotion) |
Infusion |
Capsule |
API |
Producting&Packing
Address:
Yuexiu District, Guangzhou, Guangdong, China
Business Type:
Manufacturer/Factory
Business Range:
Chemicals, Health & Medicine
Management System Certification:
ISO 9001, GMP
Company Introduction:
ABT is a group company integrating R&D, production and trade, with more than 20 years of global business experience in the pharmaceutical industry. We have an integrated production and trade supply chain from API to preparations, and have the ability to produce and develop impurity cutting- edge biotechnology products; We have an Indian manufacturing supply and sales network and have been committed to the role of a link between Chinese and Indian medicine for mutual development for over 20 years.
Our products contain:
1. Formulation products:
(1) Infusions: Registration in progress and completed, more than 10 countries and regions overseas
(2) Injections: Products are shipped to more than 10 countries and regions
(3) Tablets, capsules: Ultra- low price of Indian raw materials supply, to guarantee our quality, price advantage
2. API and Intermediate: Super low price, quality assurance, direct procurement and delivery from India
3. Impurity: Two laboratories in Guangzhou and Zhengzhou have leading R&D advantages in the industry, with more than 40 R&D personnel
4. Biological products: Hair Growth Promoter; NMN
5. Paper Making Chemical